Webdabigatran (Pradaxa) 14-17 hours (up to 34 hrs in severe renal impairment) ~ 65% Drug activity can be assessed with aPTT and/or plasma-diluted thrombin time (UWMedicine: dabigatran assay [DABIG]) If ingested within 2 hours, administer activated charcoal For life-threatening bleeding or emergency surgery, consider idarucizumab WebFor patients with moderate renal impairment (CrCl 30-50 mL/min), reduce the dose of PRADAXA Capsules to 75 mg twice daily when dronedarone or systemic ketoconazole …
Guidelines for Neuraxial Anesthesia and Anticoagulation
WebCoumadin (warfarin) will be stopped several days prior to procedure. Your physician will provide you with a stop taking date. Pradaxa (dabigatran), Xarelto (rivaroxaban) or Eliquis (apixaban) will be stopped prior to procedure. Your physician will provide you with a stop taking date. No diuretic (water pill) the morning of procedure. WebDabigatran: hold 48 hours if CrCl >80 (longer for CrCl <80). Rivaroxaban, apixaban or edoxaban: hold 48 hours if CrCl >30 (longer for CrCl <30). Antiplatelet loading pre-cath prior to coronary or structural intervention. Labs: CBC, BMP, coags (PTT and INR). Consider isotonic IVF before, during and after procedure to reduce risk of contrast ... cummings street mbc
PRE-PROCEDURE ANTICOAGULANT HOLD TIMES
WebJul 23, 2024 · A normal or slightly elevated aPTT (dabigatran) or antifactor Xa activity (rivaroxaban, apixaban) is reassuring. A patient's INR is not a reliable measure Rivaroxaban (Xeralto) withhold for 3-4 days 5 days in CKD stage 3 7 days in CKD stage 4 Apixaban (Elquis) withhold 3-4 days if renal disease present >/= 5 days Dabigatran (Pradaxa) WebMar 25, 2012 · Hemonc Today Dabigatran is an oral anticoagulant - a synthetic thrombin inhibitor – that is approved in the United States for the prevention of stroke and … WebPradaxa® (dabigatran etexilate) is a prescription medicine that is used to: reduce the risk of stroke and blood clots in adults who have a medical condition called atrial fibrillation that is not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. cummings street church memphis tn livestream