WebFLSC IgG1 binds two domains on CCR5, the N-terminus and the second extracellular loop, lowering the levels of available CCR5 viral attachment sites. Furthermore, FLSC IgG1 synergizes with Maraviroc (MVC), the only licensed CCR5 antagonist. In this study, we used both microscopy and functional assays to address the mechanistic aspects of the ... WebLSC / FLSC is available in a variety of sheath and explosive materials. Core-loads (explosive per unit length) range from 8 grains per foot to 800 plus grains per foot. Detonation velocities, depending on the sheath and explosive type, ranges from 6,000 to over 8,000 meters/second. .
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