Web5 de jan. de 2024 · We identified that the Bcl-2/adenovirus E1B 19-kDa interacting protein (bnip3) functions as a regulator of mitophagy in M. nipponense and demonstrated that hif-1α activates bnip3 by binding to the bnip3 promoter. Hif-1α knockdown suppressed the expression of multiple mitophagy-related genes, and prawns with hif-1α knockdown … Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt.
Autophagy regulates hypoxia-induced osteoclastogenesis through …
Web4 de abr. de 2011 · The data also showed that the activation of autophagy under hypoxic conditions was caused by up-regulated expression of hypoxia-inducible factor-1α (HIF … WebAnti-HIF-1 alpha antibody [EP1215Y] (ab51608) View more associated products. Overview. Product name. HIF1a + BNIP3 Hypoxia Response Human Flow Cytometry Kit. Detection method. ... BNIP3 readout. HeLa … greenbushes office park
BNIP3L - an overview ScienceDirect Topics
Web18 de jan. de 2024 · In the neonatal corpus luteum, HIF-1α up-regulated BNIP3 expressions, which contributed to the autophagic initiation by disrupting beclin1 from Bcl-2/beclin1 … WebFigure 1. HIF-1a staining of HeLa cells. Anti-HIF-1a antibody [EPR16897] (ab179483) was used at 1/50 dilution with goat anti-rabbit IgG (Alexa Fluor ® 488) secondary antibody. … Web13 de jul. de 2024 · Hypoxia-inducible factor-1 (HIF-1) dependent expressions of DRP1 and phosphorylated DRP1 and mitophagy-related protein BNIP3 were significantly upregulated in hypoxia-surviving HCC cells (Fig. 1e). greenbushes pool camping